THCV
THCV, Tetrahydrocannabivarin ist das propyl¬seitige Analog von Δ⁹-THC: Die kürzere C₃-Seitenkette führt zu einem teils gegenläufigen Wirkprofil. In frischem Pflanzenmaterial liegt vor allem Tetrahydrocannabivarin¬säure (THCVA) vor; nach Decarboxylierung entsteht das neutrale THCV. Dosisabhängig wirkt es biphasisch: Bei niedrigen Konzentrationen blockiert es CB1-Rezeptoren und kann appetithemmend sowie potenziell gewichtsreduzierend wirken; in höheren Dosen fungiert es als CB1-Partialagonist mit mild psycho¬aktiven Effekten. Zudem zeigt THCV moderate Affinität zu CB2 und TRP-Kanälen, was in präklinischen Studien auf antidiabetische, antikonvulsive und entzündungshemmende Eigenschaften hinweist. Häufig findet man es in süd- und ostafrikanischen Cannabis¬kultivaren, wo es bis zu mehreren Prozent auftreten kann und das Gesamtwirkprofil des Kultivars mitprägt.
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enua Pharma GmbH
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50827 Cologne
Germany
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enua Pharma GmbH
Vitalisstraße 67
50827 Cologne
Germany
Customer service
We are available for you from Monday to Friday from 9:00 AM to 5:00 PM.
Phone number
Knowledge
enua Pharma GmbH
Vitalisstraße 67
50827 Cologne
Germany
Customer service
We are available for you from Monday to Friday from 9:00 AM to 5:00 PM.
Phone number
Knowledge